USS Independence (1776 brig), was a brigantine built at Kingston, Massachusetts in mid-1776. The brig served in the Massachusetts State Navy and cruised off New England until captured by the Royal Navy in early 1777.
USS Independence (1776 sloop), was a 10 gun sloop commissioned in September 1776 and wrecked in 1778.
USS Independence (1814), was the first ship of the line in the Navy launched 22 June 1814 and finally being used as a receiving ship until being decommissioned 3 November 1912.
USS Independence (SP-3676), was a steamer commissioned 16 November 1918 and decommissioned 20 March 1919. She was later renamed Neville and used in Word War II.
USS Independence (CVL-22), was a light aircraft carrier, launched 22 August 1942; decommissioned 28 August 1946 and sunk during weapon testing 29 January 1951.
USS Independence (CV-62), was an aircraft carrier commissioned in 1959 and decommissioned in 1998.
USS Independence (LCS-2), is a Littoral Combat Ship currently under construction.
The USS Independence (NCC-77199) was an Interceptor-class ship that served in Starfleet. She was the fifth Starfleet ship to bear the name and part of the Allied 8th Fleet. Commissioned on Stardate 52789, The Independence was meant to see combat in the Dominion War. Only two months later, however, the war ended.